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Single-cell nanobody-based profiles of multiple epigenetic modalities and chromatin velocity

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Nanobody–Tn5 transposase fusion proteins enable detection of two histone marks and open chromatin regions at the same time, with single-cell resolution.

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Fig. 1: Multimodal chromatin profiling by nano-CT.

References

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This is a summary of: Bartosovic, M. & Castelo-Branco, G. Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag. Nat. Biotechnol. https://doi.org/10.1038/s41587-022-01535-4 (2022).

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Single-cell nanobody-based profiles of multiple epigenetic modalities and chromatin velocity. Nat Biotechnol 41, 767–768 (2023). https://doi.org/10.1038/s41587-022-01596-5

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