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GENOME EDITING

Improving CRISPR tools by elucidating DNA repair

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Genome-editing tools are optimized by identifying genes that affect DNA repair.

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Fig. 1: CRISPR screening identifies genes affecting genome editing and improves genome editors.

References

  1. Koblan, L. W. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-00938-z (2021).

  2. Hussmann, J. A. et al. Cell 184, 5653–5669 (2021).

    Article  CAS  Google Scholar 

  3. Chen, P. J. et al. Cell 184, 5635–5652 (2021).

    Article  CAS  Google Scholar 

  4. Komor, A. C. et al. Nature 533, 420–424 (2016).

    Article  CAS  Google Scholar 

  5. Anzalone, A. V. et al. Nature 576, 149–157 (2019).

    Article  CAS  Google Scholar 

  6. Kim, H. K. et al. Nat. Methods 14, 153–159 (2017).

    Article  CAS  Google Scholar 

  7. Arbab, M. et al. Cell 182, 463–480 (2020).

    Article  CAS  Google Scholar 

  8. Song, M. et al. Nat. Biotechnol. 38, 1037–1043 (2020).

    Article  CAS  Google Scholar 

  9. Gilbert, L. A. et al. Cell 154, 442–451 (2013).

    Article  CAS  Google Scholar 

  10. Gilbert, L. A. et al. Cell 159, 647–661 (2014).

    Article  CAS  Google Scholar 

  11. Nelson, J. W. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-01039-7 (2021).

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Correspondence to Hyongbum Henry Kim.

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Lim, J.M., Kim, H.H. Improving CRISPR tools by elucidating DNA repair. Nat Biotechnol 39, 1512–1514 (2021). https://doi.org/10.1038/s41587-021-01149-2

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