Genome-editing tools are optimized by identifying genes that affect DNA repair.
References
Koblan, L. W. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-00938-z (2021).
Hussmann, J. A. et al. Cell 184, 5653–5669 (2021).
Chen, P. J. et al. Cell 184, 5635–5652 (2021).
Komor, A. C. et al. Nature 533, 420–424 (2016).
Anzalone, A. V. et al. Nature 576, 149–157 (2019).
Kim, H. K. et al. Nat. Methods 14, 153–159 (2017).
Arbab, M. et al. Cell 182, 463–480 (2020).
Song, M. et al. Nat. Biotechnol. 38, 1037–1043 (2020).
Gilbert, L. A. et al. Cell 154, 442–451 (2013).
Gilbert, L. A. et al. Cell 159, 647–661 (2014).
Nelson, J. W. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-021-01039-7 (2021).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lim, J.M., Kim, H.H. Improving CRISPR tools by elucidating DNA repair. Nat Biotechnol 39, 1512–1514 (2021). https://doi.org/10.1038/s41587-021-01149-2
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41587-021-01149-2
- Springer Nature America, Inc.