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Reading amino acids in a nanopore

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In a step toward nanopore sequencing of proteins, an aerolysin pore discriminates many of the proteinogenic amino acids.

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Fig. 1: Electrical recognition of amino acid residues.

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Authors and Affiliations

  1. Department of Chemistry, Institute of Structural and Molecular Biology, University College London, London, UK

    Stefan Howorka

  2. Department of Physics and Astronomy, University of California, Irvine, Irvine, California, USA

    Zuzanna S. Siwy

Authors
  1. Stefan Howorka
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  2. Zuzanna S. Siwy
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Corresponding authors

Correspondence to Stefan Howorka or Zuzanna S. Siwy.

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Competing interests

S.H. holds patents on protein and DNA nanopores that have been licensed to Oxford Nanopore Technologies.

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Howorka, S., Siwy, Z.S. Reading amino acids in a nanopore. Nat Biotechnol 38, 159–160 (2020). https://doi.org/10.1038/s41587-019-0401-y

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