Skip to main content
SpringerLink
Log in

A shot in the arm for new antibiotics

  • Correspondence
  • Published:

From Nature Biotechnology

View current issue Submit your manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

IQVIA data from Alan Carr, Needham; FDA; CMS.

References

  1. Centers for Medicare and Medicaid Services. FY 2020 IPPS Final Rule, CMS-1716-F (2019); https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/AcuteInpatientPPS/FY2020-IPPS-Final-Rule-Home-Page-Items/FY2020-IPPS-Final-Rule-Regulations.html?DLPage=1&DLEntries=10&DLSort=0&DLSortDir=ascending

  2. Verma, S. Aligning payment and prevention to drive antibiotic innovation for Medicare beneficiaries. Health Aff. (Millwood) https://www.healthaffairs.org/do/10.1377/hblog20190802.505113/full/ (2019).

  3. Outterson, K. Innovative ways to pay for new antibiotics will help fight superbugs. STAT https://www.statnews.com/2018/04/11/innovation-new-antibiotics-fight-superbugs/ (2018).

  4. Wennberg, J. E., McPherson, K. & Caper, P. N. Engl. J. Med. 311, 295–300 (1984).

    Article  CAS  Google Scholar 

  5. Morrisey, M. A., Sloan, F. A. & Valvona, J. Health Aff. (Millwood) 7, 52–64 (1988).

    Article  CAS  Google Scholar 

  6. Liu, Z., Dow, W. H. & Norton, E. C. J. Health Econ. 23, 129–155 (2004).

    Article  Google Scholar 

  7. Chhabra, K. R., Ibrahim, A. M., Thumma, J. R., Ryan, A. M. & Dimick, J. B. Health Aff. (Millwood) 38, 1207–1215 (2019).

    Article  Google Scholar 

  8. Clyde, A. T., Bockstedt, L., Farkas, J. A. & Jackson, C. Health Aff. (Millwood) 27, 1632–1641 (2008).

    Article  Google Scholar 

  9. Rex, J. H. et al. Clin. Infect. Dis. 65, 141–146 (2017).

    Article  Google Scholar 

  10. Powers, J. H., Evans, S. R. & Kesselheim, A. S. Br. Med. J. 360, k587 (2018).

    Article  Google Scholar 

  11. Social Security Act §1886(a)(4) (1989).

  12. DISARM Act (2019).

  13. Ardal, C.O. et al. Revitalizing the antibiotic pipeline: stimulating innovation while driving sustainable use and global access. DRIVE-AB Final Report (European Commission, Innovative Medicines Initiative, 2018).

  14. Outterson, K. et al. PLoS Med. 13, e1002043 (2016).

    Article  Google Scholar 

  15. Outterson, K., Powers, J. H., Daniel, G. W. & McClellan, M. B. Health Aff. (Millwood) 34, 277–285 (2015).

    Article  Google Scholar 

  16. Outterson, K. Cardozo Law Rev. 31, 613 (2010).

    Google Scholar 

  17. Kesselheim, A. S. & Outterson, K. Yale J. Health Policy Law Ethics 11, 101–167 (2011).

    PubMed  Google Scholar 

  18. O’Neill, J. Tackling drug-resistant infections globally: final report and recommendations (Review on Antimicrobial Resistance, London, 2016).

    Google Scholar 

  19. Clift, C. et al. Towards a new global business model for antibiotics: report from the Chatham House Working Group on New Antibiotic Business Models (London, 2015).

Download references

Author information

Authors and Affiliations

  1. Boston University, Boston, MA, USA

    Kevin Outterson

Authors
  1. Kevin Outterson
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kevin Outterson.

Ethics declarations

Competing interests

K.O. is the executive director of CARB-X, funded by three governments (US, UK and Germany) and two foundations (Wellcome Trust and Gates). CARB-X is a non-profit accelerator of preclinical and phase 1 antibacterial research that awards grants worldwide.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Outterson, K. A shot in the arm for new antibiotics. Nat Biotechnol 37, 1110–1112 (2019). https://doi.org/10.1038/s41587-019-0279-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41587-019-0279-8

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation