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Evolution of CAR T-cell immunotherapy in terms of patenting activity

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An analysis of published patent applications in chimeric antigen receptor (CAR) T-cell immunotherapy allows insight into the development of this emerging technology.

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Fig. 1
Fig. 2: Geographical analysis of CAR T-cell patenting activity.
Fig. 3
Fig. 4: Patenting evolution of the top five CAR T-cell applicants.
Fig. 5: Network node map of CAR T-cell applicants.
Fig. 6: CAR T-cell patent value analysis.

Change history

  • 09 April 2019

    In the version of this article initially published online, the abstract read “dedvelopment” instead of “development” as a result of a publisher error. The error has been corrected in the print, PDF and HTML versions of this article.

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Acknowledgements

This article is based on a study that was commissioned by the European Patent Office with the aim of demonstrating to readers outside the disciplines of patent analysis and CAR T-cell immunotherapy how patent information can be used to gain insight and competitive advantages about a specific technological field. The authors thank F. Aslund, P. Bumb and D. Manu from the European Patent Office for their support in the classification identification process and assistance for fine-tuning the search strategy. The opinions expressed in this article are those of the authors and not necessarily those of their employers.

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Author notes

  1. These authors contributed equally: Björn Jürgens, Nigel S. Clarke.

Authors and Affiliations

  1. CITPIA PATLIB Center, Agency for Innovation and Development of Andalusia, Seville, Spain

    Björn Jürgens

  2. European Patent Office, Vienna, Austria

    Nigel S. Clarke

Authors
  1. Björn Jürgens
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  2. Nigel S. Clarke
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Correspondence to Nigel S. Clarke.

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Jürgens, B., Clarke, N.S. Evolution of CAR T-cell immunotherapy in terms of patenting activity. Nat Biotechnol 37, 370–375 (2019). https://doi.org/10.1038/s41587-019-0083-5

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