Extirpative surgery for all patients with upper tract urothelial carcinoma (UTUC) risks overtreatment and associated morbidity. Endoscopic approaches are particularly applicable for low-risk disease albeit with the potential for ipsilateral upper tract recurrence. Adjuvant and ablative intracavitary therapies are current and future strategies that could improve disease outcomes and increase adoption of kidney preservation for UTUC.
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J.D.R. declares that he is a study site investigator for the OLYMPUS trial (NCT02793128) and a member of the strategic advisory board for Urogen Pharma Ltd.
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Raman, J.D. Adjuvant and ablative therapies for low-risk UTUC: avenues to enhance kidney preservation. Nat Rev Urol 17, 433–434 (2020). https://doi.org/10.1038/s41585-020-0338-4
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DOI: https://doi.org/10.1038/s41585-020-0338-4
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