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RHEUMATOID ARTHRITIS

Towards the patient-centred care of rheumatoid arthritis

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New research reveals that outcomes for patients with rheumatoid arthritis are affected less by pre-existing comorbid conditions than by socioeconomic factors. Future research should address the mechanisms of this relationship and develop holistic treatment approaches that reduce disparities attributed to socioeconomic status.

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Fig. 1: Directed acyclic graph showing complex relationships between comorbidities, clinical and patient-reported outcomes and patient sociodemographics in rheumatoid arthritis.

References

  1. Baillet, A. et al. Points to consider for reporting, screening for and preventing selected comorbidities in chronic inflammatory rheumatic diseases in daily practice: a EULAR initiative. Ann. Rheum. Dis. 75, 965–973 (2016).

    Article  Google Scholar 

  2. Busby, A. D. et al. The role of comorbidities alongside patient and disease characteristics on long-term disease activity in RA using UK inception cohort data. Rheumatology https://doi.org/10.1093/rheumatology/keac139 (2022).

    Article  PubMed  Google Scholar 

  3. Mikuls, T. R. Co-morbidity in rheumatoid arthritis. Best Pract. Res. Clin. Rheumatol. 17, 729–752 (2003).

    Article  Google Scholar 

  4. Zaccardelli, A., Friedlander, H. M., Ford, J. A. & Sparks, J. A. Potential of lifestyle changes for reducing the risk of developing rheumatoid arthritis: is an ounce of prevention worth a pound of cure? Clin. Ther. 41, 1323–1345 (2019).

    Article  Google Scholar 

  5. Barton, J. L. et al. Racial and ethnic disparities in disease activity and function among persons with rheumatoid arthritis from university-affiliated clinics. Arthritis Care Res. 63, 1238–1246 (2011).

    Article  CAS  Google Scholar 

  6. Izadi, Z. et al. Socioeconomic disparities in functional status in a national sample of patients with rheumatoid arthritis. JAMA Netw. Open 4, e2119400 (2021).

    Article  Google Scholar 

  7. Lewer, D. et al. Premature mortality attributable to socioeconomic inequality in England between 2003 and 2018: an observational study. Lancet Public Health 5, e33–e41 (2020).

    Article  Google Scholar 

  8. Pearl, J. On the consistency rule in causal inference: axiom, definition, assumption, or theorem? Epidemiology 21, 872–875 (2010).

    Article  Google Scholar 

  9. Burgers, L. E., Raza, K. & van der Helm-van Mil, A. H. Window of opportunity in rheumatoid arthritis- definitions and supporting evidence: from old to new perspectives. RMD Open 5, e000870 (2019).

    Article  Google Scholar 

  10. Harrold, L. R. et al. Cost-related medication nonadherence in older patients with rheumatoid arthritis. J. Rheumatol. 40, 137–143 (2013).

    Article  Google Scholar 

Download references

Acknowledgements

G.S. is supported by the Russell/Engleman Medical Research Center for Arthritis.

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Correspondence to Zara Izadi.

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Izadi, Z., Schmajuk, G. Towards the patient-centred care of rheumatoid arthritis. Nat Rev Rheumatol 18, 367–368 (2022). https://doi.org/10.1038/s41584-022-00794-4

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