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Hyperferritinaemia and hyperuricaemia — a causal connection?

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A variety of comorbidities of gout exist, but most of these associations are not causally linked. Mendelian randomization analysis of genome-wide association study data now suggests that iron overload might increase serum uric acid levels and hence the risk of gout flares.

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Authors and Affiliations

  1. Rheumatology Department, Hôpital Lariboisière, INSERM U1132, 2 rue Ambroise Paré, Paris, France

    Pascal Richette & Augustin Latourte

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  1. Pascal Richette
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  2. Augustin Latourte
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Correspondence to Pascal Richette.

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The authors declare no competing interests.

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Richette, P., Latourte, A. Hyperferritinaemia and hyperuricaemia — a causal connection?. Nat Rev Rheumatol 14, 628–629 (2018). https://doi.org/10.1038/s41584-018-0100-y

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