An understanding of the biochemical processes underlying Parkinson disease (PD) will be essential for the development of disease-modifying therapies. In a recent study, a novel biochemical phenotype of the disease was identified from analysis of inducible pluripotent stem cell-derived dopaminergic neurons from individuals with young-onset PD.
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Schapira, A.H.V., Morris, H.R. Pathogenetic insights into young-onset Parkinson disease. Nat Rev Neurol 16, 245–246 (2020). https://doi.org/10.1038/s41582-020-0343-5
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DOI: https://doi.org/10.1038/s41582-020-0343-5
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