Outdated knowledge of arterial perfusion territories still guides clinical decisions and management in acute and chronic stroke. In a new study, application of machine learning techniques provides more detail than ever before, laying the foundation for improved stroke management and new research.
References
Berkhemer, O. A. et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N. Engl. J. Med. 372, 11–20 (2015).
Berman, S. A., Hayman, L. A. & Hinck, V. C. Correlation of CT cerebral vascular territories with function: 3. Middle cerebral artery. AJR Am. J. Roentgenol. 142, 1035–1040 (1984).
Shi, Y. & Wardlaw, J. M. Update on cerebral small vessel disease: a dynamic whole-brain disease. Stroke Vasc. Neurol. 1, 83–92 (2016).
Wang, Y. et al. Voxel-wise density-based clustering of infarct lesions topographic distribution: the first step towards a stroke atlas for the brain. Neuroimage Clin. https://doi.org/10.1016/j.nicl.2019.101981 (2019).
Hartkamp, N. S., Petersen, E. T., De Vis, J. B., Bokkers, R. P. & Hendrikse, J. Mapping of cerebral perfusion territories using territorial arterial spin labeling: techniques and clinical application. NMR Biomed. 26, 901–912 (2013).
Kim, D. E. et al. Mapping the supratentorial cerebral arterial territories using 1160 large artery infarcts. JAMA Neurol. 76, 72–80 (2019).
Weaver, N. A. et al. The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: design and multicenter pilot study. Alz. Dement. 11, 310–326 (2019).
Payabvash, S., Noorbaloochi, S. & Qureshi, A. I. Topographic assessment of acute ischemic changes for prognostication of anterior circulation stroke. J. Neuroimaging 27, 227–231 (2017).
Payabvash, S. et al. Regional ischemic vulnerability of the brain to hypoperfusion: the need for location specific computed tomography perfusion thresholds in acute stroke patients. Stroke 42, 1255–1260 (2011).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Vernooij, M.W. A data-driven update of arterial perfusion territories. Nat Rev Neurol 15, 624–625 (2019). https://doi.org/10.1038/s41582-019-0267-0
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41582-019-0267-0
- Springer Nature Limited