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The ethics of genetic testing for kidney diseases

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From Nature Reviews Nephrology

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Growing genomic knowledge has provided immense insight into the aetiology and mechanisms of kidney diseases but raises ethical issues that risk the successful implementation of genomic medicine. We highlight such issues in two contexts: the return of individual genetic results from nephrology research and preimplantation genetic diagnosis for heritable kidney diseases.

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References

  1. Koenig, B. A. Hastings Cent. Rep. 44 (4), 33–34 (2014).

    Article  Google Scholar 

  2. Duncan, R. E. & Young, M.-A. Per. Med. 10, 589–600 (2013).

    Article  CAS  Google Scholar 

  3. Berns, J. S. Clin. J. Am. Soc. Nephrol. 5, 490–496 (2010).

    Article  Google Scholar 

  4. Yu, J.-H. et al. Am. J. Med. Genet. A 161A, 1064–1072 (2013).

    Article  Google Scholar 

  5. Passmore, S. R. et al. Public Health Genomics 22, 215–226 (2019).

    Article  Google Scholar 

  6. Sabatello, M. et al. Public Health Genomics https://doi.org/10.1159/000506599 (2020).

    Article  PubMed  Google Scholar 

  7. Swift, O. et al. Genet. Test. Mol. Biomarkers 20, 741–746 (2016).

    Article  Google Scholar 

  8. Groopman, E. E. et al. N. Engl. J. Med. 380, 142–151 (2019).

    Article  CAS  Google Scholar 

  9. Montini, G. et al. J. Nephrol. 31, 95–102 (2018).

    Article  Google Scholar 

  10. De Rechter, S. et al. PLoS ONE 12, e0185779 (2017).

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported by NHGRI grant K01HG008653 (M.S.) and an investigator award from the Renal Research Institute (H.M.R.).

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Authors and Affiliations

  1. Center for Research on Ethical, Legal & Social Implications of Psychiatric, Neurologic & Behavioral Genetics, Department of Psychiatry, Columbia University, New York, NY, USA

    Maya Sabatello

  2. Division of Nephrology, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, NY, USA

    Hila Milo Rasouly

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  1. Maya Sabatello
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  2. Hila Milo Rasouly
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Correspondence to Maya Sabatello.

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Competing interests

M.S. is a member of the All of Us Research Program’s Institutional Review Board. H.M.R. declares no competing interests.

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Sabatello, M., Milo Rasouly, H. The ethics of genetic testing for kidney diseases. Nat Rev Nephrol 16, 619–620 (2020). https://doi.org/10.1038/s41581-020-0294-5

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