The generation of local immune responses in organs requires a coordinated effort, not just from immune cells, but also from ‘structural’ cells such as epithelial cells, endothelial cells and fibroblasts. New insights gained from profiling these cells across organs in the mouse emphasizes the important contribution of this structural cell network to organ immunity.
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Tuong, Z.K., Clatworthy, M.R. Organ immune responses — don’t forget the structural cells. Nat Rev Nephrol 16, 570–571 (2020). https://doi.org/10.1038/s41581-020-00334-x
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DOI: https://doi.org/10.1038/s41581-020-00334-x
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