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GLOMERULAR DISEASE

MENTOR heralds a new era of therapy for membranous nephropathy

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The MENTOR trial reported that rituximab is superior to ciclosporin for remission of nephrotic syndrome in patients with membranous nephropathy. Rituximab is better tolerated than other treatments but, as up to 40% of patients did not respond to rituximab, alternative immunosuppressive therapies may still be required for a substantial minority of patients.

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Fig. 1: Suggested initial therapy for the treatment of membranous nephropathy.

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  1. Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, UK

    Aikaterini Nikolopoulou & Megan Griffith

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  1. Aikaterini Nikolopoulou
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  2. Megan Griffith
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Correspondence to Megan Griffith.

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The authors declare no competing interests.

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Nikolopoulou, A., Griffith, M. MENTOR heralds a new era of therapy for membranous nephropathy. Nat Rev Nephrol 15, 664–666 (2019). https://doi.org/10.1038/s41581-019-0200-1

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