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Elucidating the transmission landscape of the human microbiome

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From Nature Reviews Gastroenterology & Hepatology

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In a study published in Nature, new data have highlighted the bacterial strain-level sharing rates of mother–offspring pairs, twins, families, cohabiting individuals and individuals within a population, as well as those between different populations, providing a comprehensive view of the transmission landscape of the intestinal and oral microbiome in humans. These findings highlight the need to reassess diseases currently considered to be non-communicable and underscore the importance of considering social structure and transmissibility in the design of microbial studies.

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Fig. 1: Transmission patterns of the human microbiome.

References

  1. Gacesa, R. et al. Environmental factors shaping the gut microbiome in a Dutch population. Nature 604, 732–739 (2022).

    Article  CAS  PubMed  Google Scholar 

  2. Berg, G. et al. Microbiome definition re-visited: old concepts and new challenges. Microbiome 8, 103 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Sorbara, M. T. & Pamer, E. G. Microbiome-based therapeutics. Nat. Rev. Microbiol. 20, 365–380 (2022).

    Article  CAS  PubMed  Google Scholar 

  4. Eckburg, P. B. et al. Diversity of the human intestinal microbial flora. Science 308, 1635–1638 (2005).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Lloréns-Rico, V. & Raes, J. Tracking humans and microbes. Nature 569, 632–633 (2019).

    Article  PubMed  Google Scholar 

  6. Brito, I. L. et al. Transmission of human-associated microbiota along family and social networks. Nat. Microbiol. 4, 964–971 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Browne, H. P., Neville, B. A., Forster, S. C. & Lawley, T. D. Transmission of the gut microbiota: spreading of health. Nat. Rev. Microbiol. 15, 531–543 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Suzuki, T. A. et al. Codiversification of gut microbiota with humans. Science 377, 1328–1332 (2022).

    Article  CAS  PubMed  Google Scholar 

  9. Metwaly, A., Reitmeier, S. & Haller, D. Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders. Nat. Rev. Gastroenterol. Hepatol. 19, 383–397 (2022).

    Article  PubMed  Google Scholar 

  10. Valles-Colomer, M. et al. The person-to-person transmission landscape of the gut and oral microbiomes. Nature 614, 125–135 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Correspondence to Dirk Haller.

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Metwaly, A., Haller, D. Elucidating the transmission landscape of the human microbiome. Nat Rev Gastroenterol Hepatol 20, 415–416 (2023). https://doi.org/10.1038/s41575-023-00780-5

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