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LIVER TRANSPLANTATION

Bridging transplantation with beads in paediatric acute liver failure

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From Nature Reviews Gastroenterology & Hepatology

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In a new study, cryopreserved human hepatocytes retrieved from livers deemed unsuitable for transplantation were thawed and encapsulated into alginate microbeads and then infused into the peritoneal cavity of a group of children with acute liver failure who were awaiting liver transplantation.

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Fig. 1: Hepatocyte transplantation for children with ALF.

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Authors and Affiliations

  1. Department of Pediatric Gastroenterology and Hepatology, University of Pittsburgh Medical Center Children’s Hospital of Pittsburgh, Pittsburgh, USA

    Patrick J. McKiernan & Robert H. Squires

Authors
  1. Patrick J. McKiernan
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  2. Robert H. Squires
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Correspondence to Robert H. Squires.

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Competing interests

R.H.S. received a royalty fee for contributions to UpToDate. P.J.M. declares no competing interests.

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McKiernan, P.J., Squires, R.H. Bridging transplantation with beads in paediatric acute liver failure. Nat Rev Gastroenterol Hepatol 17, 197–198 (2020). https://doi.org/10.1038/s41575-020-0281-0

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