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Bone marrow adipose tissue function — is space a constraint?

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Bone marrow adipose tissue secretes adipokines and is involved in glucose and lipid metabolism. The confined bone marrow cavity could partially explain the resistance of bone marrow adipose tissue to insulin-mediated glucose uptake and its role in systemic energy regulation.

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Authors and Affiliations

  1. Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA

    Wei Shen

  2. Institute of Human Nutrition, Columbia University Irving Medical Center, New York, NY, USA

    Wei Shen

  3. Columbia Magnetic Resonance Research Center (CMRRC), Columbia University, New York, NY, USA

    Wei Shen

  4. Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA

    Steven B. Heymsfield

Authors
  1. Wei Shen
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  2. Steven B. Heymsfield
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Correspondence to Wei Shen.

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The authors declare no competing interests.

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Shen, W., Heymsfield, S.B. Bone marrow adipose tissue function — is space a constraint?. Nat Rev Endocrinol 16, 543–544 (2020). https://doi.org/10.1038/s41574-020-0400-6

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  • DOI: https://doi.org/10.1038/s41574-020-0400-6

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