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CARDIOVASCULAR ENDOCRINOLOGY

Vitamin D supplementation: a novel therapy for aldosteronism?

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Available evidence demonstrates a crosstalk between the renin–angiotensin and the parathyroid hormone–vitamin D systems. A new study suggests that vitamin D supplementation can lower systolic blood pressure and plasma aldosterone levels in patients with primary aldosteronism.

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Fig. 1: Model of how vitamin D deficiency or insufficiency could lead to secondary hyperparathyroidism.

References

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Authors and Affiliations

  1. Hypertension Unit, Department of Medicine (DIMED), University of Padova, Padova, Italy

    Gian Paolo Rossi & Livia Lenzini

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  1. Gian Paolo Rossi
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  2. Livia Lenzini
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Correspondence to Gian Paolo Rossi.

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The authors declare no competing interests.

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Rossi, G.P., Lenzini, L. Vitamin D supplementation: a novel therapy for aldosteronism?. Nat Rev Endocrinol 16, 303–304 (2020). https://doi.org/10.1038/s41574-020-0359-3

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