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The microbiome as a determinant of racial and ethnic cancer disparities

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Fig. 1: Examples of multilevel exposures that may influence the gut microbiome and, in turn, contribute to cancer disparities.

References

  1. Giaquinto, A. N. Cancer statistics for African American/Black People 2022. CA Cancer J. Clin. 72, 202–229 (2022).

    Article  PubMed  Google Scholar 

  2. Siegel, R. L., Miller, K. D., Wagle, N. S. & Jemal, A. Cancer statistics, 2023. CA Cancer J. Clin. 73, 17–48 (2023).

    Article  PubMed  Google Scholar 

  3. El Tekle, G. & Garrett, W. S. Bacteria in cancer initiation, promotion and progression. Nat. Rev. Cancer 23, 600–618 (2023).

    Article  CAS  PubMed  Google Scholar 

  4. Deschasaux, M. et al. Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography. Nat. Med. 24, 1526–1531 (2018).

    Article  CAS  PubMed  Google Scholar 

  5. Yazici, C. et al. Race-dependent association of sulfidogenic bacteria with colorectal cancer. Gut 66, 1983–1994 (2017).

    Article  CAS  PubMed  Google Scholar 

  6. Amato, K. R. et al. The human gut microbiome and health inequities. Proc. Natl Acad. Sci. USA 118, e2017947118 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Song, M., Chan, A. T. & Sun, J. Influence of the gut microbiome, diet, and environment on risk of colorectal cancer. Gastroenterology 158, 322–340 (2020).

    Article  CAS  PubMed  Google Scholar 

  8. Stierman, B. et al. National Health and Nutrition Examination Survey 2017–March 2020 Prepandemic Data Files — Development of Files and Prevalence Estimates for Selected Health Outcomes; National Health Statistics Reports no. 158 (2021).

  9. Wirbel, J. et al. Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer. Nat. Med. 25, 679–689 (2021).

    Article  Google Scholar 

  10. Vogtmann, E. et al. Representative oral microbiome data for the US population: the National Health and Nutrition Examination Survey. Lancet Microbe 4, e60–e61 (2023).

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Cancer Epidemiology Department, Division of Population Sciences, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

    Doratha Byrd

  2. Department of Nutrition Science, Purdue University, West Lafayette, IN, USA

    Patricia Wolf

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  1. Doratha Byrd
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  2. Patricia Wolf
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Correspondence to Doratha Byrd.

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Competing interests

D.B. serves on the board of directors at Scalar International.

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Byrd, D., Wolf, P. The microbiome as a determinant of racial and ethnic cancer disparities. Nat Rev Cancer 24, 89–90 (2024). https://doi.org/10.1038/s41568-023-00638-7

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