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Expanding oesophageal cancer research and care in eastern Africa

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The African Esophageal Cancer Consortium is a self-organized oesophageal cancer research consortium of more than 80 physicians and scientists working at ten sites in nine countries of eastern and southern Africa. We study the aetiology of this highly fatal cancer and are expanding the clinical capacity to improve cancer care.

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References

  1. Arnold, M., Ferlay, J., van Berge Hengouwen, M. I. & Soerjomataram, I. Global burden of esophageal and gastric cancer by histology and subsite in 2018. Gut 69, 1564–1571 (2020).

    Article  Google Scholar 

  2. Parker, R. K., Dawsey, S. M., Abnet, C. C. & White, R. E. Frequent occurrence of esophageal cancer in young people in western Kenya. Dis. Esoph. 23, 128–135 (2010).

    Article  CAS  Google Scholar 

  3. Van Loon, K. et al. The African Esophageal Cancer Consortium (AfrECC): a call to action. J. Global. Oncol. 4, 1–9 (2018).

    Google Scholar 

  4. Mwachiro, M. M. et al. Indoor wood combustion, carcinogenic exposure and esophageal cancer in south-west Kenya. Environ. Int. 152, 106485 (2021).

    Article  CAS  Google Scholar 

  5. Mmbaga, B. T. et al. Missing and decayed teeth, oral hygiene and dental staining in relation to esophageal cancer risk: ESCCAPE case-control study in Kilimanjaro, Tanzania. Int. J. Cancer 148, 2416–2428 (2020).

    Article  Google Scholar 

  6. Mmbaga, E. J. et al. A case-control study to evaluate environmental and lifestyle risk factors for esophageal cancer in Tanzania. Cancer Epidemiol. Biomarkers Prev. 30, 305–316 (2021).

    Article  Google Scholar 

  7. Mushi, B. P. et al. Improving access to self-expanding metal stents for patients with esophageal cancer in Eastern Africa: a stepwise implementation strategy. JCO Glob. Oncol. 7, 118–126 (2021).

    Article  Google Scholar 

  8. Mwachiro, M. M. et al. Esophageal squamous dysplasia is common in asymptomatic Kenyans: a prospective, community based, cross-sectional study. Am. J. Gastroenterol. 111, 500–507 (2016).

    Article  CAS  Google Scholar 

  9. Mwachiro, M. M. et al. Gastrointestinal endoscopy capacity in Eastern Africa. Endosc. Int. Open 9, E1827–36 (2021).

    Article  Google Scholar 

  10. Middleton, D. R. S. et al. Minimally invasive esophageal sponge cytology sampling is feasible in a Tanzanian community setting. Int. J. Cancer 148, 1208–1218 (2021).

    Article  CAS  Google Scholar 

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Acknowledgements

This work was supported in part by the Intramural Research Program of the National Cancer Institute, NIH.

Author information

Authors and Affiliations

  1. National Cancer Institute, Rockville, MD, USA

    Christian C. Abnet, Yingxi Chen & Sanford M. Dawsey

  2. University of California, San Francisco, San Francisco, CA, USA

    Geoffrey C. Buckle & Katherine Van Loon

  3. University of Zambia, Lusaka, Zambia

    Violet Kayamba & Paul Kelly

  4. Tenwek Hospital, Bomet, Kenya

    Michael M. Mwachiro & Russell E. White

  5. University of Malawi, Blantyre, Malawi

    Charles Dzamalala

  6. Mayo Clinic, Phoenix, AZ, USA

    David E. Fleischer

  7. Kamuzu Central Hospital, Lilongwe, Malawi

    Bongani Kaimila & Gift Mulima

  8. University of the Witwatersrand, Johannesburg, South Africa

    Christopher Mathew

  9. King’s College London, London, UK

    Christopher Mathew

  10. International Agency for Research on Cancer, Lyon, France

    Valerie McCormack & Joachim Schüz

  11. The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA

    Stephen J. Meltzer

  12. Moi University, Eldoret, Kenya

    Diana Menya

  13. Queen’s University Belfast, Belfast, UK

    Daniel Middleton

  14. Kilimanjaro Clinical Research Institute, Moshi, Tanzania

    Blandina T. Mmbaga

  15. Muhimbili University of Health and Allied Sciences, West Upanga, Tanzania

    Elia Mmbaga, Beatrice Mushi & Msiba Selekwa

  16. University of Cape Town, Cape Town, Republic of South Africa

    M. Iqbal Parker

  17. Mayo Clinic, Rochester, MN, USA

    Mark D. Topazian

  18. Muhimbili National Hospital, Dar es Salaam, Tanzania

    Yona Ringo

Consortia

The African Esophageal Cancer Consortium

  • Christian C. Abnet
  • , Geoffrey C. Buckle
  • , Yingxi Chen
  • , Sanford M. Dawsey
  • , Violet Kayamba
  • , Michael M. Mwachiro
  • , Charles Dzamalala
  • , David E. Fleischer
  • , Bongani Kaimila
  • , Paul Kelly
  • , Christopher Mathew
  • , Valerie McCormack
  • , Stephen J. Meltzer
  • , Diana Menya
  • , Daniel Middleton
  • , Blandina T. Mmbaga
  • , Elia Mmbaga
  • , Gift Mulima
  • , Beatrice Mushi
  • , M. Iqbal Parker
  • , Msiba Selekwa
  • , Mark D. Topazian
  • , Yona Ringo
  • , Joachim Schüz
  • , Katherine Van Loon
  •  & Russell E. White

Corresponding authors

Correspondence to Christian C. Abnet or Michael M. Mwachiro.

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Competing interests

The authors declare no competing interests.

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Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of these organizations.

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The African Esophageal Cancer Consortium. Expanding oesophageal cancer research and care in eastern Africa. Nat Rev Cancer 22, 253–254 (2022). https://doi.org/10.1038/s41568-022-00458-1

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  • DOI: https://doi.org/10.1038/s41568-022-00458-1

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