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Effects of cholesterol on biomolecular corona

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Cholesterol levels in biological fluids are shown to change the composition of the protein corona affecting the biological fate of nanoparticles.

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Fig. 1: Schematics showing the critical role of cholesterol in biomolecular corona formation at the surface of nanoparticles and their interactions with biosystems.

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Authors and Affiliations

  1. Laboratory of Advanced Biomaterials, the John Curtin School of Medical Research, Australian National University, Canberra, Australia

    Negar Mahmoudi

  2. Australian National University College of Engineering & Computer Science, Canberra, Australia

    Negar Mahmoudi

  3. Department of Radiology and Precision Health Program, Michigan State University, East Lansing, MI, USA

    Morteza Mahmoudi

Authors
  1. Negar Mahmoudi
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  2. Morteza Mahmoudi
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Correspondence to Morteza Mahmoudi.

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Competing interests

M.M. discloses that he is a co-founder and director of the Academic Parity Movement (www.paritymovement.org), a non-profit organization dedicated to addressing academic discrimination, violence and incivility; he also is an advisor for and shareholder in Partners in Global Wound Care (PGWC), and a co-founder of and shareholder in NanoServ Corp. and Targets’ Tip Corp.; and he receives royalties/honoraria for his published books, plenary lectures and licensed patents.

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Mahmoudi, N., Mahmoudi, M. Effects of cholesterol on biomolecular corona. Nat. Nanotechnol. 18, 974–976 (2023). https://doi.org/10.1038/s41565-023-01423-1

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