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Viral pathogenesis

SARS and synapses

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SARS-CoV-2 infection can be associated with ‘brain fog’ and persistent neurologic disease, especially in the elderly, with the possibility of direct viral particle interference with normal synaptic transmission.

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Fig. 1: A role for SARS-CoV-2 and synaptic transmission.

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Author information

Authors and Affiliations

  1. Center for Neurotherapeutics Discovery, Department of Neurology, Pediatrics, Neuroscience, Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA

    Harris A. Gelbard

  2. Department of Chemistry, University of Rochester, Rochester, NY, USA

    Wesley Chiang

  3. Center for Neurotherapeutics Discovery, University of Rochester Medical Center, Rochester, NY, USA

    Wesley Chiang

Authors
  1. Harris A. Gelbard
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  2. Wesley Chiang
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Correspondence to Harris A. Gelbard.

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The authors declare no competing interests.

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Gelbard, H.A., Chiang, W. SARS and synapses. Nat Microbiol 9, 1163–1164 (2024). https://doi.org/10.1038/s41564-024-01685-y

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