Exoglycosidases isolated from the mucolytic gut bacteria Akkermansia muciniphila bring enzymatic conversion of A and B blood group erythrocytes to blood group O a step closer.
References
Clausen, H. & Olsson, M. L. Nat. Microbiol. 4, 1426–1427 (2019).
Jensen, M. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-024-01663-4 (2024).
Goldstein, J., Siviglia, G., Hurst, R., Lenny, L. & Reich, L. Science 215, 168–170 (1982).
Kruskall, M. S. et al. Transfusion 40, 1290–1298 (2000).
Clausen, H. et al. Biochem. Biophys. Res. Commun. 124, 523–529 (1984).
Clausen, H., Levery, S. B., Nudelman, E., Tsuchiya, S. & Hakomori, S. Proc. Natl Acad. Sci. USA 82, 1199–1203 (1985).
Clausen, H., Levery, S. B., Kannagi, R. & Hakomori, S. J. Biol. Chem. 261, 1380–1387 (1986).
Clausen, H., Holmes, E. & Hakomori, S. J. Biol. Chem. 261, 1388–1392 (1986).
Rahfeld, P. et al. Nat. Microbiol. 4, 1475–1485 (2019).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Satchwell, T.J., Di Bartolo, N. & Toye, A.M. Gut microorganism enzymes unlock universal blood. Nat Microbiol 9, 1161–1162 (2024). https://doi.org/10.1038/s41564-024-01682-1
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41564-024-01682-1
- Springer Nature Limited