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Antimicrobial resistance

Siderophores mediate antibiotic resistance

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Pseudomonas aeruginosa protects itself, and its neighbours, from the cephalosporin cefiderocol through production of the siderophore pyoverdine.

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Fig. 1: Emergence of cross-protection by MDR P. aeruginosa through pyoverdine production.

References

  1. Wu, W., Jin, Y., Bai, F. & Jin, S. in Molecular Medical Microbiology 2nd edn (eds Tang, Y.-W. et al.) 753–767 (Academic Press, 2015).

  2. Montero, M. M. et al. J. Clin. Med. 9, 514 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Pachori, P., Gothalwal, R. & Gandhi, P. Genes Dis. 6, 109–119 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Bassetti, M. et al. Lancet Infect. Dis. 21, 226–240 (2021).

    Article  CAS  PubMed  Google Scholar 

  5. Karakonstantis, S., Rousaki, M. & Kritsotakis, E. I. Antibiotics 11, 723 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Holland, M., Bjanes, E., Nizet, V. & Dillon, N. J. Antimicrob. Chemother. 77, 433–442 (2022).

    Article  CAS  PubMed  Google Scholar 

  7. Dillon, N. et al. eBioMedicine 46, 193–201 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Turner, K. H., Wessel, A. K., Palmer, G. C., Murray, J. L. & Whiteley, M. Proc. Natl Acad. Sci. USA 112, 4110–4115 (2015).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  9. Ipe, D. S. & Ulett, G. C. J. Microbiol. Methods 127, 164–171 (2016).

    Article  PubMed  Google Scholar 

  10. Galdino, A. C. M. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-024-01601-4 (2024).

    Article  PubMed  Google Scholar 

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Correspondence to Nicholas Dillon.

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Khan, F.Z., Palmer, K. & Dillon, N. Siderophores mediate antibiotic resistance. Nat Microbiol 9, 587–588 (2024). https://doi.org/10.1038/s41564-024-01624-x

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