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FUNGAL GENETICS

Telomere transposon takeover in Cryptococcus

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Identification and analysis of mutator strains in the human fungal pathogen Cryptococcus neoformans show that natural loss of RNA interference triggers massive accumulation of Cnl1 retroelements at subtelomeric regions.

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Fig. 1: Flow diagram of screening approach and key findings.

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Authors and Affiliations

  1. Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA

    Manning Y. Huang & Hiten D. Madhani

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  1. Manning Y. Huang
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  2. Hiten D. Madhani
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Correspondence to Hiten D. Madhani.

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The authors declare no competing interests.

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Huang, M.Y., Madhani, H.D. Telomere transposon takeover in Cryptococcus. Nat Microbiol 7, 1108–1109 (2022). https://doi.org/10.1038/s41564-022-01189-7

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  • DOI: https://doi.org/10.1038/s41564-022-01189-7

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