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ANTIVIRALS

Longing for HIV protection

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Antibodies that potently neutralize highly diverse HIV-1 variants offer great potential for therapy and prevention. Passive administration of HIV-specific neutralizing antibodies genetically modified to have a long serum half-life has now been shown to confer long-lasting protection from infection in the rhesus macaque model.

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Fig. 1: Goals for the effective implementation of a passive bNAb immunization.

References

  1. Gautam, R. et al. Nature 533, 105–109 (2016).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  2. Gautam, R. et al. Nat. Med. https://doi.org/10.1038/s41591-018-0001-2 (2018).

  3. Ko, S. Y. et al. Nature 514, 642–645 (2014).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  4. Ledgerwood, J. E. et al. Clin. Exp. Immunol. 182, 289–301 (2015).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Caskey, M. et al. Nature 522, 487–491 (2015).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  6. Caskey, M. et al. Nat. Med. 23, 185–191 (2017).

    Article  PubMed  PubMed Central  CAS  Google Scholar 

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Correspondence to Guido Silvestri.

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Zanoni, M., Palesch, D. & Silvestri, G. Longing for HIV protection. Nat Microbiol 3, 648–649 (2018). https://doi.org/10.1038/s41564-018-0169-8

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