Functional and structural studies highlight the remarkable evolution and features of the typhoid toxin from Salmonella Typhi. This reveals that attachment of the toxin to specific N-glycan chains accounts for its tropism for selected human tissues.
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Bourdoulous, S., Lemichez, E. Decoding glycan recognition by bacterial toxins. Nat Microbiol 3, 124–126 (2018). https://doi.org/10.1038/s41564-018-0107-9
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DOI: https://doi.org/10.1038/s41564-018-0107-9
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