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Phaged and confused by biofilm matrix

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Bacterial biofilms fabricate an extracellular amyloid fibre network that intimately links cells together and inhibits the ability of bacteriophages to penetrate the biofilm.

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Fig. 1: Phage diffusion into the centre of a biofilm can be discouraged by curli-mediated cell packing.

References

  1. Chauret, C. Virulence 6, 593–601 (2011).

    Article  Google Scholar 

  2. Kackar, S., Suman, E. & Kotian, M. S. Indian J. Med. Microbiol. 35, 80–84 (2017).

    Article  Google Scholar 

  3. Hara, S., Koike, I., Terauchi, K., Kamiya, H. & Tanoue, E. Mar. Ecol. Prog. Ser. 145, 269–277 (1996).

    Article  Google Scholar 

  4. Vidakovic, L., Singh, P. K., Hartmann, R., Nadell, C. D. & Drescher, K. Nat. Microbiol. https://doi.org/10.1038/s41564-017-0050-1 (2017)

    Article  Google Scholar 

  5. Kostakioti, M., Hadjifrangiskou, M. & Hultgren, S. J. Cold Spring Harb. Perspect. Med. 4, a010306 (2013).

    Google Scholar 

  6. Zhou, Y. et al. J. Biol. Chem. 287, 35092–35103 (2012).

    Article  CAS  Google Scholar 

  7. DePas, W. H. et al. Proc. Natl Acad. Sci. USA 7, 2629–2634 (2012).

    Google Scholar 

  8. Serra, D. O., Richter, A. M. & Hengge, R. J. Bacteriol. 24, 5540–5554 (2013).

    Article  Google Scholar 

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Correspondence to Matthew R. Chapman.

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Price, J.E., Chapman, M.R. Phaged and confused by biofilm matrix. Nat Microbiol 3, 2–3 (2018). https://doi.org/10.1038/s41564-017-0078-2

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