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The development of cryo-EM and how it has advanced microbiology

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The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Richard Henderson and Joachim Frank for the development of cryo-electron microscopy, a technique for high-resolution structural determination of biomolecules in solution that has provided unprecedented insight into the biology of microorganisms.

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Fig. 1: Principles of cryo-electron microscopy.

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Authors and Affiliations

  1. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA

    Catherine M. Oikonomou & Grant J. Jensen

  2. Howard Hughes Medical Institute, Pasadena, CA, USA

    Grant J. Jensen

Authors
  1. Catherine M. Oikonomou
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  2. Grant J. Jensen
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Correspondence to Grant J. Jensen.

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The authors declare no competing financial interests.

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Oikonomou, C.M., Jensen, G.J. The development of cryo-EM and how it has advanced microbiology. Nat Microbiol 2, 1577–1579 (2017). https://doi.org/10.1038/s41564-017-0073-7

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