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Lymphatics drain nanoparticles from tumours

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Lymphatic vessels within and near to tumours facilitate nanoparticle transport out of tumours, with ramifications in the design and implementation of next-generation clinical cancer nanomedicines.

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Fig. 1: Lymphatic drainage of nanoparticles from tumours.

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Authors and Affiliations

  1. Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Meghan J. O’Melia

  2. George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA

    Susan N. Thomas

  3. Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA

    Susan N. Thomas

  4. Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA

    Susan N. Thomas

  5. Winship Cancer Institute, Emory University, Atlanta, GA, USA

    Susan N. Thomas

Authors
  1. Meghan J. O’Melia
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  2. Susan N. Thomas
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Correspondence to Susan N. Thomas.

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The authors declare no competing interests.

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O’Melia, M.J., Thomas, S.N. Lymphatics drain nanoparticles from tumours. Nat. Mater. 22, 1287–1288 (2023). https://doi.org/10.1038/s41563-023-01701-2

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  • DOI: https://doi.org/10.1038/s41563-023-01701-2

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