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DNA NANOSTRUCTURES

Nanodevices for cancer vaccination

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An elaborate DNA origami tubular nanodevice encapsulating antigens and adjuvants protects mice from cancer through tumour-specific immunomodulation.

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Fig. 1: Subcutaneous administration of a tubular DNA origami nanodevice vaccine for robust antigen-specific immune response against tumours.

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Authors and Affiliations

  1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P. R. China

    Hongjun Li & Zhen Gu

  2. Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA

    Zhen Gu

Authors
  1. Hongjun Li
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  2. Zhen Gu
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Correspondence to Zhen Gu.

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The authors declare no competing interests.

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Li, H., Gu, Z. Nanodevices for cancer vaccination. Nat. Mater. 20, 286–287 (2021). https://doi.org/10.1038/s41563-021-00941-4

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  • DOI: https://doi.org/10.1038/s41563-021-00941-4

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