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Cancer nanomedicine

A nanoparticle’s pathway into tumours

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New evidence now suggests that the dominant mechanism of extravasation of nanoparticles into solid tumours may be through an active process of endothelial transcytosis.

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Fig. 1: Mechanisms of nanoparticle tumour extravasation.

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Authors and Affiliations

  1. John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA

    Irene de Lázaro & David J. Mooney

  2. Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA

    Irene de Lázaro & David J. Mooney

Authors
  1. Irene de Lázaro
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  2. David J. Mooney
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Correspondence to David J. Mooney.

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de Lázaro, I., Mooney, D.J. A nanoparticle’s pathway into tumours. Nat. Mater. 19, 486–487 (2020). https://doi.org/10.1038/s41563-020-0669-9

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