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Dendritic cell tracking and modulation

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In situ metabolic labelling and targeted modulation of dendritic cells has been achieved using a hydrogel system in combination with covalent capture of antigens and adjuvants, facilitating improved tumour-specific immune response.

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Fig. 1: Illustration of the strategy for metabolic labelling of dendritic cells and priming of T cells.

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Authors and Affiliations

  1. Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA

    Joshua M. Gammon & Christopher M. Jewell

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  1. Joshua M. Gammon
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  2. Christopher M. Jewell
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Correspondence to Christopher M. Jewell.

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Competing statement

C.M.J. is an employee of the Veteran Affairs Maryland Health Care System. The views reported above do not reflect the views of the Department of Veterans Affairs or the United States Government. C.M.J. has an equity position in Cellth Systems, LLC, and Avidea Technologies.

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Gammon, J.M., Jewell, C.M. Dendritic cell tracking and modulation. Nat. Mater. 19, 1134–1135 (2020). https://doi.org/10.1038/s41563-020-00828-w

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