Skip to main content

Advertisement

SpringerLink
Log in

INFLAMMATORY BOWEL DISEASE

Materials modulate immunity and gut microbiome

  • News & Views
  • Published:

From Nature Materials

View current issue Submit your manuscript

In a murine model of acute colitis, hyaluronic acid–bilirubin-based nanomaterials have been shown to modulate immune response and the gut microbiome, as well as restore the epithelial barrier.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Nano-aggregated HABN restores gut homeostasis, microbiome and innate immune responses in IBD.

References

  1. Danese, S. & Fiocchi, C. N. Engl. J. Med. 365, 1713–1725 (2011).

    Article  CAS  Google Scholar 

  2. Lee, Y. et al. Nat. Mater. https://doi.org/10.1038/s41563-019-0462-9 (2019).

  3. Forster, S. C. et al. Nat. Biotechnol. 37, 186–192 (2019).

    Article  CAS  Google Scholar 

  4. Lloyd-Price, J. et al. Nature 550, 61–66 (2017).

    Article  CAS  Google Scholar 

  5. Neurath, M. F. Nat. Rev. Gastroenterol. Hepatol. 14, 269–278 (2017).

    Article  CAS  Google Scholar 

  6. Longhi, M. S. et al. JCI Insight 2, e92791 (2017).

    Article  Google Scholar 

  7. Lee, Y. et al. Angew. Chem. Int. Ed. Engl. 55, 7460–7463 (2016).

    Article  CAS  Google Scholar 

  8. Mosquera, M. J. et al. Sci. Adv. 5, eaav9788 (2019).

    Article  CAS  Google Scholar 

  9. Vijay-Kumar, M. et al. Science 328, 228–231 (2010).

    Article  CAS  Google Scholar 

  10. Bernardo, D. et al. Eur. J. Immunol. 42, 1337–1353 (2012).

    Article  CAS  Google Scholar 

  11. Neurath, M. F. Nat. Immunol. 20, 970–979 (2019).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sibley School of Mechanical Engineering, Cornell University, Ithaca, NY, USA

    Ankur Singh

  2. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA

    Ankur Singh

  3. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, USA

    Ankur Singh

  4. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA

    Ankur Singh

Authors
  1. Ankur Singh
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ankur Singh.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Singh, A. Materials modulate immunity and gut microbiome. Nat. Mater. 19, 3–4 (2020). https://doi.org/10.1038/s41563-019-0557-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41563-019-0557-3

  • Springer Nature Limited

Search

Navigation