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Tissue Regeneration

A pulpy story

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Over-expression of a transcriptional factor, Alx3, has been shown to revitalize the regenerative capacity of adult progenitor cells to promote enhanced stromal vascularization and formation of parenchymal dental pulp tissue in vivo.

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Fig. 1: Diagram of a mature molar tooth.
Fig. 2: Mechanisms of dentin repair.

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Authors and Affiliations

  1. Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Sarah E. Millar

  2. Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Sarah E. Millar

  3. Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Sarah E. Millar

Authors
  1. Sarah E. Millar
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Correspondence to Sarah E. Millar.

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Millar, S.E. A pulpy story. Nat. Mater. 18, 530–531 (2019). https://doi.org/10.1038/s41563-019-0372-x

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