The existence of trade-offs between traits under selection is a fundamental concept in evolutionary biology. Analysis of a densely sampled collection of adaptive mutations in yeast reveals that no single mutation can allow it to overcome detected trade-offs between key traits under selection.
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Gifford, D.R. Life on the frontline reveals constraints. Nat Ecol Evol 3, 1501–1502 (2019). https://doi.org/10.1038/s41559-019-1010-3
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DOI: https://doi.org/10.1038/s41559-019-1010-3
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