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Influenza evolution with little host selection

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Influenza viruses undergo rapid antigenic evolution. Analysis of a large dataset of influenza virus sequences, using host age as a proxy for immune experience, shows no evidence for immune positive selection driving antigenic evolution in individual infected humans.

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Author information

Authors and Affiliations

  1. Department of Pathobiological Sciences, University of Wisconsin School of Veterinary Medicine, Madison, WI, USA

    Katarina M. Braun & Thomas C. Friedrich

  2. Wisconsin National Primate Research Center, Madison, WI, USA

    Thomas C. Friedrich

Authors
  1. Katarina M. Braun
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  2. Thomas C. Friedrich
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Corresponding author

Correspondence to Thomas C. Friedrich.

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The authors declare no competing interests.

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Braun, K.M., Friedrich, T.C. Influenza evolution with little host selection. Nat Ecol Evol 3, 159–160 (2019). https://doi.org/10.1038/s41559-018-0782-1

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