Complexity is a hallmark of biological systems, but scientific experiments are typically conducted in simplified conditions. Now, diverse polymers that mimic the local environments of complex biological mixtures have been shown to improve protein folding, stability and function.
References
Fulton, A. B. Cell 30, 345–347 (1982).
Minton, A. P. J. Cell Sci. 119, 2863–2869 (2006).
Ruan, Z. et al. Nature 615, 251–258 (2023).
Panganiban, B. et al. Science 359, 1239–1243 (2018).
Hilburg, S. L., Ruan, Z., Xu, T. & Alexander-Katz, A. Macromolecules 53, 9187–9199 (2020).
Jiang, T. et al. Nature 577, 216–220 (2020).
Neuman, K. C. & Nagy, A. Nat. Methods 5, 491–505 (2008).
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Gudinas, A.P., Mai, D.J. Polymeric protagonists for biological processes. Nat. Chem. 15, 751–752 (2023). https://doi.org/10.1038/s41557-023-01219-9
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DOI: https://doi.org/10.1038/s41557-023-01219-9
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