Nitrous oxide is traditionally considered to be an inert molecule, and methods for its activation and utilization are currently limited. Now, a strategy has been developed — involving an organometallic Baeyer–Villiger step — for the conversion of aryl halides to phenols under mild conditions, using N2O as the oxygen source.
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Chen, JJ., Huang, HM. N2O revalorization. Nat. Chem. 14, 846–848 (2022). https://doi.org/10.1038/s41557-022-01007-x
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DOI: https://doi.org/10.1038/s41557-022-01007-x
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