Bacterial communication is a potential strategy to control bacterial behaviours and thus, attenuate pathogen infectivity; however, identifying the signalling molecules that regulate communication pathways is challenging. Now, a robust strategy to rapidly identify previously unknown signalling peptides has been developed. This approach provides a means to map out and decipher bacterial signalling mechanisms.
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References
Gless, B. H. et al. Nat. Chem. https://doi.org/10.1038/s41557-019-0256-3 (2019).
Novick, R. P. & Geisinger, E. Annu. Rev. Genet. 42, 541–564 (2008).
Thoendel, M., Kavanaugh, J. S., Flack, C. E. & Horswill, A. R. Chem. Rev. 111, 117–151 (2011).
Le, K. Y. & Otto, M. Front. Microbiol. 6, 1174 (2015).
Wang, B. & Muir, T. W. Cell Chem. Biol. 23, 214–224 (2016).
Rutherford, S. T. & Bassler, B. L. Cold Spring Harb. Perspect. Med. 2, a012427 (2012).
Cook, L. C. & Federle, M. J. Fems Microbiol. Rev. 38, 473–492 (2014).
Dawson, P. E. & Kent, S. B. H. Annu. Rev. Biochem. 69, 923–960 (2000).
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McBrayer, D.N., Tal-Gan, Y. Deciphering bacterial signalling. Nat. Chem. 11, 398–399 (2019). https://doi.org/10.1038/s41557-019-0265-2
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DOI: https://doi.org/10.1038/s41557-019-0265-2
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