What does an actively transcribing genomic locus look like? A recent study has taken advantage of large and highly expressed mammalian genes and used microscopy to find out. The discovery sheds light on transcription and its effect on chromosome structure and the spatial organization of gene loci.
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Friman, E.T., Bickmore, W.A. The sight of transcription. Nat Cell Biol 24, 284–285 (2022). https://doi.org/10.1038/s41556-022-00865-4
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DOI: https://doi.org/10.1038/s41556-022-00865-4
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