The vascular system, plastic and positioned in the vicinity of tissues, is an undervalued regulator of adult stem cells. Two studies now show that the vascular-like Drosophila trachea is reshaped after intestinal damage or tumour formation and that this remodelling is required for compensatory intestinal stem cell proliferation and tumour growth.
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Gervais, L., Bardin, A.J. Tracheal remodelling supports stem cells. Nat Cell Biol 23, 580–582 (2021). https://doi.org/10.1038/s41556-021-00695-w
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DOI: https://doi.org/10.1038/s41556-021-00695-w
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