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CELL MIGRATION

Migrasomes take center stage

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Migrasomes are a recently discovered type of extracellular vesicles that are characteristically generated along retraction fibers in migrating cells. Two studies now show how migrasomes are formed and how they function in the physiologically relevant context of the developing zebrafish embryo.

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Fig. 1: Migration-depended mechanical force triggers migrasome formation.
Fig. 2: Mesendoderm-derived migrasomes regulate clustering of DFCs.

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Correspondence to Carl-Philipp Heisenberg.

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Tavano, S., Heisenberg, CP. Migrasomes take center stage. Nat Cell Biol 21, 918–920 (2019). https://doi.org/10.1038/s41556-019-0369-3

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