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STEM CELLS

Long noncoding RNAs in gut stem cells

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The intestinal crypt has become the prototype compartment to investigate adult stem cell biology, and the list of identified intestinal stem cell (ISC) markers is already extensive. A comprehensive study now uncovers an additional layer in ISC regulation by introducing long noncoding RNA lncGata6 to the stem cell repertoire.

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Fig. 1: Function of intestinal stem cell specific lncGata6.

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Correspondence to Pantelis Hatzis or Hugo J. G. Snippert.

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Hatzis, P., Snippert, H.J.G. Long noncoding RNAs in gut stem cells. Nat Cell Biol 20, 1106–1107 (2018). https://doi.org/10.1038/s41556-018-0208-y

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