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STEM CELLS

Muscling toward therapy with ERBB3 and NGFR

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To overcome the finite supply of muscle stem cells available for cell therapy, a study now describes a strategy for obtaining an unlimited source of myogenic progenitors derived from human pluripotent cells. Two neuronal cell surface receptors facilitate the selection of a population with enhanced regenerative potential.

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Fig. 1: Neuronal markers facilitate isolation of myogenic progenitors derived from hiPSCs.

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Authors and Affiliations

  1. Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford School of Medicine, Stanford, CA, USA

    Andrew T. V. Ho & Helen M. Blau

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  1. Andrew T. V. Ho
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  2. Helen M. Blau
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Correspondence to Helen M. Blau.

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The authors declare no competing financial interests.

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Ho, A.T.V., Blau, H.M. Muscling toward therapy with ERBB3 and NGFR. Nat Cell Biol 20, 6–7 (2018). https://doi.org/10.1038/s41556-017-0015-x

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  • DOI: https://doi.org/10.1038/s41556-017-0015-x

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