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Single-cell analysis of ductal differentiation

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A microwell chip facilitates the differentiation of aggregates of human induced pluripotent stem cells into pancreatic-duct-like organoids and the characterization of the differentiation process at the single-cell level.

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Fig. 1: Differentiation of pancreatic-duct-like organoids in a microwell chip.

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Authors and Affiliations

  1. Division of Gastroenterology, Department of Medicine, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

    Jason R. Pitarresi

  2. Division of Digestive and Liver Diseases, Department of Medicine, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA

    Jason R. Pitarresi & Anil K. Rustgi

Authors
  1. Jason R. Pitarresi
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  2. Anil K. Rustgi
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Correspondence to Anil K. Rustgi.

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The authors declare no competing interests.

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Pitarresi, J.R., Rustgi, A.K. Single-cell analysis of ductal differentiation. Nat Biomed Eng 5, 785–786 (2021). https://doi.org/10.1038/s41551-021-00782-1

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