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NEUROMODULATION

Multifunctional optofluidic brain probes

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Smartphone-controlled optofluidic neural implants with replaceable and replenishable plug-like drug cartridges enable the selective wireless manipulation of brain circuits in rodents via chronic pharmacology and photostimulation.

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Fig. 1: Refillable optofluidic brain implants for neuromodulation.
Fig. 2: Potential integration of optofluidic brain probes and other diagnostic and drug-delivery systems.

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Authors and Affiliations

  1. John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA

    John F. Zimmerman

  2. Department of Chemistry, the James Franck Institute, the Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA

    Bozhi Tian

Authors
  1. John F. Zimmerman
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  2. Bozhi Tian
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Corresponding authors

Correspondence to John F. Zimmerman or Bozhi Tian.

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Zimmerman, J.F., Tian, B. Multifunctional optofluidic brain probes. Nat Biomed Eng 3, 596–597 (2019). https://doi.org/10.1038/s41551-019-0439-7

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