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Seeing whole-tumour heterogeneity

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Light-sheet microscopy reveals 3D tumour heterogeneity in optically cleared paraffin-embedded tumour samples.

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Fig. 1: Advantages of whole-tissue imaging over traditional histology.
Fig. 2: The DIPCO pipeline for phenotyping entire FFPE tumour samples in three dimensions.

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Correspondence to Boyan K. Garvalov or Ali Ertürk.

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Garvalov, B.K., Ertürk, A. Seeing whole-tumour heterogeneity. Nat Biomed Eng 1, 772–774 (2017). https://doi.org/10.1038/s41551-017-0150-5

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