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Organs-on-chips: Filtration enabled by differentiation

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The efficient generation of mature podocytes from induced pluripotent stem cells makes possible the recapitulation of renal blood filtration on a chip.

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Figure 1: Recapitulation of the function of the glomerular capillary wall on a chip.

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Authors and Affiliations

  1. Department of Physiology, National University of Singapore, 2 Medical Drive, 117593, Singapore

    Eliza Li Shan Fong & Hanry Yu

  2. Department of Biomedical Engineering, National University of Singapore, 4 Engineering Drive 3, 117583, Singapore

    Eliza Li Shan Fong & Hanry Yu

  3. Mechanobiology Institute, National University of Singapore, 5A Engineering Drive 1, 117411, Singapore

    Hanry Yu

  4. Institute of Bioengineering and Nanotechnology, A*STAR, 31 Biopolis Way, 138669, Singapore

    Hanry Yu

Authors
  1. Eliza Li Shan Fong
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  2. Hanry Yu
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Correspondence to Hanry Yu.

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Fong, E., Yu, H. Organs-on-chips: Filtration enabled by differentiation. Nat Biomed Eng 1, 0074 (2017). https://doi.org/10.1038/s41551-017-0074

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