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Noise-cancelling translation syncs cellular clocks

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Theory and single-cell experiments outline a new role for upstream open reading frames in buffering cellular heterogeneity in protein abundance at the translation level.

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Fig. 1: Model for uORF-mediated noise reduction in protein abundance via translational repression.

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Authors and Affiliations

  1. University of California, Berkeley, Berkeley, CA, USA

    Simon Alamos

  2. Lawrence Berkeley National Laboratory, Berkeley, CA, USA

    Simon Alamos

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  1. Simon Alamos
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Correspondence to Simon Alamos.

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Alamos, S. Noise-cancelling translation syncs cellular clocks. Nat. Plants 8, 455–456 (2022). https://doi.org/10.1038/s41477-022-01143-9

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