Salicylic acid (SA) is an essential hormone for plant immune responses. In Arabidopsis, SA is perceived by two groups of receptors, NPR1 and NPR3/4, which play opposite roles in regulating defence gene expression. How SA binds to its receptors is now revealed by crystal structure analysis.
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We thank N. Zheng for discussions, K. Ao for careful reading of the manuscript and K. T. Devendrakumar for assistance with making the figure.
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Li, X., Zhang, Y. A structural view of salicylic acid perception. Nat. Plants 6, 1197–1198 (2020). https://doi.org/10.1038/s41477-020-0741-0
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DOI: https://doi.org/10.1038/s41477-020-0741-0
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